Molecular and Cellular Biology of Pathogenic Trypanosomatids (Frontiers in Parasitology) (PDF)
by Maria Isabel N. Cano (Editor) and Marcelo Santos da Silva_0
Trypanosomatids , the parasites that cause leishmaniasis , Chagas disease and African trypanosomiasis , infect millions of individuals worldwide who live in tropical locations every year .
The WHO classifies these illnesses as neglected tropical diseases because they lack effective vaccinations , have few effective treatments and carry a high risk of developing drug-resistant parasite strains . These all pose serious problems for public health systems and place a heavy financial load on them . Recent years have seen the emergence of numerous research projects with the goal of uncovering parasitic molecular and cellular biology , parasite-host interactions , disease pathogenesis mechanisms and molecular mechanisms of drug resistance , all of which are crucial for the development of novel anti-parasite therapies and eradication strategies .
The developments in try panosomatid molecular and cellular biology are highlighted in this volume . Cell organization during development, genome organization and upkeep, gene expression control , nuclear and kinetoplast DNA replication , mechanisms of DNA damage repair , virulence factors and immune evasion, new techniques for molecular diagnosis , new therapeutic tools, and recombinant vaccine biology are among the subjects covered . The premedical and biological undergraduates , graduates (master’s and doctoral students) , parasitology researchers and researchers in adjacent domains will all find this monograph interesting .
See also : General , Organic and Biological Chemistry , 1st Edition (Original PDF from Publisher)
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