Molecular and Cellular Biology of Pathogenic Trypanosomatids (Frontiers in Parasitology) (PDF)

Molecular and Cellular Biology of Pathogenic Trypanosomatids (Frontiers in Parasitology) (PDF)

by Maria Isabel N. Cano (Editor) and Marcelo Santos da Silva_0

Trypanosomatids , the parasites that cause leishmaniasis , Chagas disease and African trypanosomiasis , infect millions of individuals worldwide who live in tropical locations every year .

The WHO classifies these illnesses as neglected tropical diseases because they lack effective vaccinations , have few effective treatments and carry a high risk of developing drug-resistant parasite strains . These all pose serious problems for public health systems and place a heavy financial load on them . Recent years have seen the emergence of numerous research projects with the goal of uncovering parasitic molecular and cellular biology , parasite-host interactions , disease pathogenesis mechanisms and molecular mechanisms of drug resistance , all of which are crucial for the development of novel anti-parasite therapies and eradication strategies .

The developments in try panosomatid molecular and cellular biology are highlighted in this volume . Cell organization during development, genome organization and upkeep, gene expression control , nuclear and kinetoplast DNA replication , mechanisms of DNA damage repair , virulence factors and immune evasion, new techniques for molecular diagnosis , new therapeutic tools, and recombinant vaccine biology are among the subjects covered . The premedical and biological undergraduates , graduates (master’s and doctoral students) , parasitology researchers and researchers in adjacent domains will all find this monograph interesting .

See also : General , Organic and Biological Chemistry , 1st Edition (Original PDF from Publisher)