Genetics of Human Infertility (Monographs in Human Genetics, Vol. 21) (PDF)
by M. Schmid (Series Editor) and P.H. Vogt (Editor)_0
More than one in ten couples experience infertility , which is linked to a wide range of diseases that are occasionally only detectable in the germ line . In addition to anatomical problems, immunological interference and environmental factors , its complicated etiology frequently but not always includes genetic elements .
Only genetic problems are likely to blame for close to 30% of cases of infertility . Experimental animal knockout models therefore effectively demonstrate that single or several gene abnormalities may contribute to infertility . Because it is difficult to translate these fundamental research findings into clinical investigations , genetic explanations for the great majority of infertile patients remain unknown .
Nevertheless , highly advanced molecular techniques have identified a significant number of potential genes . This book offers a thorough overview of the topic of infertility prepared by the foremost experts in this area . Basic biological , cytological and molecular research are covered , along with common and rare disorders . Human geneticists , endocrinologists , epidemiologists , zoologists and counselors who work in the fields of human genetics , infertility and assisted reproduction should all study it .
See Also: Emery’s Elements of Medical Genetics, 15th Edition (PDF)
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