Cell Biology , 4th edition (Original PDF from Publisher)
By Graham Johnson , MA , PhD , CMI , Jennifer Lippincott-Schwartz , PhD , William C. Earnshaw , PhD and Thomas D. Pollard , MD
Reader-friendly Cell Biology , Fourth Edition offers students pursuing careers in research or healthcare a succinct yet thorough basis.
Prize-winning images facilitate readers’ rapid understanding of general concepts . This well-known book has been completely revised by the authors to give readers the most recent knowledge onthe fundamentals of healthy cellular function as well as illustrations of how genetic flaws can lead to disease in humans .
The roles of intrinsically disordered polypeptides and phase separation in cellular functions , the impact of novel molecular structures on comprehension of mechanisms and the advancement of our understanding through innovative new techniques—from single cell RNA sequencing to second generation super resolution fluorescence microscopy—are some of the major new themes in the fourth edition .
Simple , comprehensible explanations give a succinct account of how cells work on a molecular level . Genome organization , gene expression and RNA processing provide the groundwork for an intuitive chapter flow that enables comprehension of all facets of cellular function and physiology . makes cellular biology more approachable for students with an interest in medicine by describing how genetic abnormalities can affect almost every cellular system and increase the risk of developing a disease in people .
Novel treatments for diseases like cystic fibrosis , heart failure , cancer and many more have been made possible by advances in cell biology. Every physiological process , including the assembly of SARS CoV-2 , the structures attaching mitotic chromosomes to microtubules, the mechanism of DNA replication and the coordination of physiological processes from synaptic transmission to cellular volume regulation , is explained by distinctive illustrations that feature realistic proportions and relationships .
covers fascinating discoveries such as how TOR kinases regulate metabolism , SMC motor proteins actively organize chromosomal DNA , novel forms of immunotherapy for the treatment of cancer , mechanisms governing fast axonal transport and their connection to neurodegenerative diseases , how the completion of DNA replication determines when a cell enters mitosis , how a series of signals determines the location of cell division and recently discovered pathways of both normal and pathological cell death . Included with the purchase is an enhanced eBook version . You can use your upgraded eBook on many devices to access all of the text , figures and references from the book .
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